Pain tossed the vial at Hades, which is the most grave mistake he ever just made, which shrunk down the god of the Underworld down to the size of a mere pebble. Pain then grabbed him and immediately placed him directly underneath his large feet on his Herc Sandals. Pain is enjoying every bit of this while also knowing that Hades is about to give him the smack down of his life the minute he returns back to normal size. Panic can't help but be mesmerized by both the size of his good friend's feet and sandals to the point where he started fondling him which Pain let him do. More than friends and all that.